Video answer: Skyrim special edition: how to start dark brotherhood (walkthrough quest remastered gameplay)
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Speaking with Aventus Aretino in his parent's home in Windhelm initiates the quest "Innocence Lost" and starts the Dark Brotherhood questline. After accepting Aretino's proposal, the Dragonborn is directed to visit Honorhall Orphanage. After killing Grelod, the children will cheer and celebrate her death.
Video answer: Skyrim master #4 - how to start the dark brotherhood quest